Semo laundry is a 24-hour laundromat serving Cape Girardeau and the surrounding Missouri area. We provide self-service coin laundry, professional wash and fold service, and convenient drop-off laundry options. Our modern facility features commercial-grade washers and dryers for all load sizes, from small loads to large comforters and bedding. Enjoy complimentary WiFi while you wait. Free parking available for all customers. Whether you need a quick self-service wash or prefer our attendant-assisted laundry service, we make doing laundry easy and convenient.
Semo laundry offers free WiFi, on-site parking, a coin changer, an on-site attendant, and RV-friendly access, making it a well-equipped option for residents in Cape Girardeau, Missouri.
Last updated: April 13, 2026
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Self-Service Coin Laundry
Modern commercial washers and dryers available for self-service laundry. Multiple load capacity options from standard to extra large machines for bulky items like comforters and sleeping bags. Coin-operated and card-payment options available for your convenience.
Professional Wash and Fold Service
Drop off your dirty laundry and let our experienced attendants handle the washing, drying, and folding. Our wash dry fold service saves you time while ensuring your clothes are properly cleaned and neatly folded. Perfect for busy professionals and families who need quality laundry service without the hassle.
Commercial-Grade Equipment
Our laundromat features high-efficiency commercial washers and dryers that clean better and dry faster than home machines. Energy-efficient equipment means lower costs and faster turnaround for your laundry needs. Multiple machine sizes accommodate everything from delicates to heavy-duty items.
Flexible Payment Options
On-site coin changer available to convert bills into quarters for our coin-operated machines. No need to worry about having exact change – we make payment easy so you can focus on getting your laundry done.
Semo laundry is open 24 hours a day, 7 days a week, making it one of the most accessible laundromats in Cape Girardeau.
Serving Cape Girardeau, Missouri at 1225 William St. Customers in the Cape Girardeau area can find Semo laundry at 1225 William St, Cape Girardeau, Missouri 63703.
This location is equipped with 7 listed amenities including free WiFi, on-site parking, coin changer.
Yes, we provide complimentary WiFi access for all customers. Connect to our network while you wait for your laundry.
Yes, we have convenient parking spaces available for our customers right outside the facility.
Yes, we have coin changing machines available to convert your bills into quarters for the washers and dryers.
Yes, we have friendly staff members available to assist you with any questions or help you may need.
Yes, our facility welcomes RV travelers with easy access and spacious parking to accommodate larger vehicles.
Products for your laundromat day
As an Amazon Associate, LaundryArchive earns from qualifying purchases.
Self-Service Coin Laundry
Modern commercial washers and dryers available for self-service laundry. Multiple load capacity options from standard to extra large machines for bulky items like comforters and sleeping bags. Coin-operated and card-payment options available for your convenience.
Professional Wash and Fold Service
Drop off your dirty laundry and let our experienced attendants handle the washing, drying, and folding. Our wash dry fold service saves you time while ensuring your clothes are properly cleaned and neatly folded. Perfect for busy professionals and families who need quality laundry service without the hassle.
Commercial-Grade Equipment
Our laundromat features high-efficiency commercial washers and dryers that clean better and dry faster than home machines. Energy-efficient equipment means lower costs and faster turnaround for your laundry needs. Multiple machine sizes accommodate everything from delicates to heavy-duty items.
Flexible Payment Options
On-site coin changer available to convert bills into quarters for our coin-operated machines. No need to worry about having exact change – we make payment easy so you can focus on getting your laundry done.
Semo laundry is open 24 hours a day, 7 days a week, making it one of the most accessible laundromats in Cape Girardeau.
Serving Cape Girardeau, Missouri at 1225 William St. Customers in the Cape Girardeau area can find Semo laundry at 1225 William St, Cape Girardeau, Missouri 63703.
This location is equipped with 7 listed amenities including free WiFi, on-site parking, coin changer.
Yes, we provide complimentary WiFi access for all customers. Connect to our network while you wait for your laundry.
Yes, we have convenient parking spaces available for our customers right outside the facility.
Yes, we have coin changing machines available to convert your bills into quarters for the washers and dryers.
Yes, we have friendly staff members available to assist you with any questions or help you may need.
Yes, our facility welcomes RV travelers with easy access and spacious parking to accommodate larger vehicles.